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商品详细分子尺寸/结构筛2 Eco筛/MD1-02-Eco/1 Ea
分子尺寸/结构筛2 Eco筛/MD1-02-Eco/1 Ea
分子尺寸/结构筛2 Eco筛/MD1-02-Eco/1 Ea
商品编号: MD1-02-ECO
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公司分类: Other_reagents
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商品介绍

Structure Screen 2 Eco Screen MD1-02-ECO

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Structure Screen 2 Eco Screen is formulated without cacodylate, azides or dioxane for the crystallization of

  • Proteins
  • Peptides
  • Nucleic acids
  • water soluble small molecules.
This classic standard sparse matrix screen lets you:
  • Determine initial crystallization condition.
  • Establish the solubility of a macromolecule in a varying range of pH and precipitants.
  • Enables screening of greater crystallization space with the enhanced buffer selection.

Keywords: Crystal Screen, Basic screen, Jancarick and Kim, Classics. Jancarik & Kim, nucleic acids, small molecules.


Originally published in 1991 by Jancarik & Kim from conditions found to be successful in the crystallization of biological macromolecules.

A comparison of three commercial sparse matrix screens, (Wooh et al, 2003) reported dramatically different results when comparing Crystal Screens and Structure Screens. In 38 cases the Structure Screens were more successful in producing crystals than the Crystal Screens while the opposite was the case in 26 formulations. The formulations are not identical as in several buffers Molecular Dimensions uses glacial acetic acid to adjust the pH rather than HCl. This formulation was chosen from current practice developed from experience at major UK research institutions.

References:

Jancarik, J & Kim, S.H.J. (1991), J.Appl.Cryst. 24, 409-411
Wooh et al, (2003), Acta Cryst , D59, 769 - 772.

Read about the Classical crystal growth screening approach to protein crystallography.Learn about Modern crystal growth screening.


品牌介绍
Molecular Dimensions 来自 digital.library.unt.edu   喜欢 0 阅读量: 1 作者: Moss, H. H 摘要: This study attempts to calculate the areas of the cross section and diameter of the CH3 group, COOH group, the length of the carbon chain, and the longtiudinal distance between carbon atoms for each of the three acids. It also attempts to develop a method of measuring the effective diameter of molecules of gases. Equations for these terms as given by MacDougall and experiments were performed and the data applied to the equation. 关键词: carbon chain carbon atoms diameter of molecules of gases
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