MemMeso™FX-96pre-filledplateMD1-87-FX
MemMeso™-optimizedscreenforLCPcrystallization.
Makesureyougetthelipidicphaseyouneedforsuccess.
DevelopedinconjunctionwiththesuccessfullaboratoryofProf.OsamuNurekiattheUniversityofTokyo,Japan,thissemi-systematicscreenhasbeendesignedtoworkinsynergywithLipidicCubicPhase(LCP),nowcommonlyusedinmembraneproteincrystallization,withoutperturbingphaseformation.
BenefitsofMemMeso™:
•OptimizedtoworkinsynergywithLipidicCubicPhase(LCP)andtheLCPcrystallizationmethod.
•Worry-FreescreeninginbothLCPandSpongePhase.
•Up-to-dateconditionsdata-minedfromcurrentreportedGPCRcrystalstructures.
•HT-formatsemi-systematicscreeningkit,containing96conditionscoveringarangeofpH,precipitantsandsalt.
•Provensuccessatcrystallizingthecrystalstructuresofeightmembraneproteins,includingthestructureofchannelrhodopsin(2012,Nature).
Todate,componentsofMemMeso™havecrystallizednofewerthaneightmembraneproteinsstructures,namely:Channelrhodopsin(2012,Nature,Vol482,p369-375),PfMATE(2013,Nature,Vol496,p247-253),NCX_Mj(2013,Science,Vol341,p168-172),GkPOT(2013,PNAS,Vol110no28,p11343-11348),andfourbacterialtransporters(manuscriptinpreparation).