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Molecular Dimensions/NR-LBD™ + NR-LBD™ Extension FX-96 pre-filled plate/MD1-34-FX/1 Ea
NR-LBD™+NR-LBD™ExtensionFX-96pre-filledplateMD1-34-FX
Arationalapproachtoscreeninginitialcrystallizationconditionsofnuclearreceptor-ligandbindingdomains(NR-LBDs).Withall96reagentsfoundtobeidealforthecrystallizationofnuclearreceptorligandbindingdomainsavailableinone96-wellblock.
FeaturesoftheNuclearReceptor-LigandBindingDomainScreen
•ThepHrangeforcrystallizationis6.0to9.0.
•IncludesawiderangeofPEGs.
•Includessodiumformate,sodiumcitrateandsodiumacetatecarboxylicacids.
•Ionicstrengthcontrolledwithsodiumchlorideandammoniumacetate.
•pHrangeisbetween6.5and8.5usingBis-Tris(pH6.5),PIPES(pH7.0),sodiumHEPES(pH7.5)andTris(pH8.0and8.5).
Thishigh-throughputkitcontains96x100µLconditionsinanSBSplate.
*NR-LBDandNR-LBDExtensionweredevelopedbyDenisZeyer,SylvieDuclaud,DinoMorasandJean-PaulRenaudatTheInstituteofGeneticsandMolecularandCellBIOLOGy,CNRS,UMR7104,Illkirch,FranceandismanufacturedunderanexclusivelicencefromCNRS,France.