Molecular Dimensions/The BCS Eco Screen/MD1-104-ECO/1 Ea-免疫在线蚂蚁淘旗下平台

当前位置：首页 > 产品中心 > Other_reagents > Molecular Dimensions/The BCS Eco Screen/MD1-104-ECO/1 Ea

商品详细Molecular Dimensions/The BCS Eco Screen/MD1-104-ECO/1 Ea

Molecular Dimensions/The BCS Eco Screen/MD1-104-ECO/1 Ea

商品编号： MD1-104-ECO

品牌： moleculardimensions

市场价： ¥0.00

美元价： 0.00

产地：美国(厂家直采)

公司：

产品分类：其他试剂

公司分类： Other_reagents

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

立即询价

商品介绍

TheBCSEcoScreenMD1-104-ECO

TheBCS(BasicChemicalSpace)ScreendevelopedattheStructuralGenomicConsortium(SGC),Oxfordhasanovelapproachtoscreening.PEGsaregroupedbymolecularweightandmixedtocreatefourPEGSmears(availabletopurchaseseparately).ThesmearscoverabroaderrangeofchemicalspacewhilereducingthenumberofPEGvariables.

ThisisanEcoversionofthatscreen,wheresodiumcacodylatehasbeenreplacedbyMES.

PEGisaneffectivecrystallizationagentduetoitsprotein-proteininteractionpromotingproperties.TheBIOLOGicalMacromolecularCrystallizationdatabaserecordsatleast20differentPEGcompoundsinfrequentuseasmacromolecularprecipitants.TheBCSScreenovercomestheimpracticalityofsamplingallPEGvarietiesthathasledtoafewvariantspredominatinginthemostcommonscreens(right).

ThebottomlineisthatintestsattheSGCwith191humanproteins,TheBCSScreenhada42%hitratewithonly96conditions.Manyoftheseproteinshadfailedtocrystallizeinotherscreens.

Thefirst24conditionsinTheBCSScreenformagridscreenofthefourPEGSmearsagainstpH(range4.5-9.5).Theremaining72conditionsconsistofasparsematrixscreeninwhichtheprecipitantisalwaysoneofthePEGSmearsbutwithavarietyofadditivesandbuffers.Theadditivesincludesomeofthemoreunusualcrystal-promotingagentssuchasrubidiumchloride(alsousefulforphasing)andammoniumnitrate.Morecommonadditivesincludingsodiumbromide(usefulforphasing)andglycerolarealsousedinthescreen.

Reference

Chaikuad,A,Knapp,SandvonDelft,K(2015).DefinedPEGsmearsasanalternativeapproachtoenhancethesearchforcrystallizationconditionsandcrystal-qualityimprovementinreducedscreens.ActaCrystallographicaF71:1627-1639.

品牌介绍

Molecular Dimensions 来自 digital.library.unt.edu  喜欢 0 阅读量： 1 作者： Moss, H. H 摘要： This study attempts to calculate the areas of the cross section and diameter of the CH3 group, COOH group, the length of the carbon chain, and the longtiudinal distance between carbon atoms for each of the three acids. It also attempts to develop a method of measuring the effective diameter of molecules of gases. Equations for these terms as given by MacDougall and experiments were performed and the data applied to the equation. 关键词： carbon chain carbon atoms diameter of molecules of gases

公司介绍

Molecular Dimensions 来自 digital.library.unt.edu  喜欢 0 阅读量： 1 作者： Moss, H. H

品牌分类

LCP公司晶体生长盒套件细胞培养产品清仓优惠添加剂筛蛋白质稳定性筛选。。。低温电磁网格蛋白质复性试剂。。。结构首饰

高通量板。。。 Uni-Pucks和配件润滑石环和活动环。。。 24个井板和井盖卡瓦。。。样品制备。。。成核剂，定相套件特殊洗涤剂。。。预填充（FX）板最佳低温冷却小分子阴离子筛冷冻屏脂质。。。准备生长结晶试剂盒结晶工具。。。磁性CryoVials CryoCaps 蛋白质复合物。。。配件硅烷介质 Cryo EM网格盒和网格盒存储荧光成像（仅限美洲）最后的机会酒吧！配件晶体结构玻璃块核受体膜蛋白。。。低温托运人，冰箱和储存杜瓦瓶... 结晶筛单试剂显微镜工具包。。。液氮冷却器透析预填板洗涤剂。。。冷冻配件所有结晶筛。。。硒标记。。。微型工具密封板和深井块核酸 EMBL/ESRF样品更换套件 Rigaku试剂。。。蛋白质表达介质。。。储备试剂。。。替代晶体安装系统特别优惠通用实验室清洁剂。。。 LCP板。。。优化提示膜蛋白非液氮冷却器可溶性蛋白质。。。分子定制结晶筛琼脂糖凝胶和DNA染色生长你的第一颗水晶书泡沫与金属杜瓦瓶... 达勒姆屏风低温保护孵化器。。。

显示分类

联络我们

服务热线：4000-520-616

（限工作日9:00-18:00）

QQ ：1570468124

手机：18915418616

官网：https://www.moleculardimensions.com